DoD Melanoma, Team Science Award | HT942525MRPTSA

Opportunity Information: Apply for HT942525MRPTSA

The DoD Melanoma, Team Science Award (Funding Opportunity Number HT942525MRPTSA) is a discretionary grant program run through the Department of the Army, U.S. Army Medical Research Acquisition Activity (USAMRAA), under CFDA 12.420. It is designed to fund hypothesis-driven melanoma research that uses a multidisciplinary, team-based approach and aims for near-term advances in melanoma science and/or patient care. The program is built around the idea that melanoma remains a complex, multi-factor disease where meaningful progress often requires combining perspectives, tools, and methods from different fields (for example, immunology, oncology, genomics, dermatology, computational biology, imaging, drug development, behavioral science, or clinical practice) to solve problems that directly influence patient outcomes.

A defining feature of this opportunity is the requirement for multiple Principal Investigators. Applicants must form a leadership team of at least two and up to three PIs who jointly design and carry out one integrated research project. Multi-institutional collaborations are explicitly encouraged, reflecting the program goal of creating synergy across organizations, disciplines, and potentially different therapeutic or research areas. If the project is selected for funding, each PI will be listed on a separate award made to their respective organization(s), which reinforces the expectation that each PI has a distinct and accountable role within the shared project plan.

For FY25, the application process includes a gatekeeping step: after submitting a required pre-application, teams must receive an invitation before they are allowed to submit a full application. Only the Initiating PI submits the pre-application on behalf of the team. At the full application stage, all PIs must submit application materials, but the Partnering PI(s) submit a shortened, role-specific package focused on the work they will lead. This structure signals that the program expects a single cohesive project with clearly defined, complementary contributions rather than loosely connected parallel studies.

The award emphasizes impact and translatability, and it encourages, though does not require, collaboration with the melanoma consumer community (such as patients, survivors, caregivers, or advocacy groups). The intent is to keep research aligned with real-world needs, improve the relevance of research questions and outcomes, and increase the likelihood that findings can be implemented in ways that benefit the communities affected by melanoma.

Key administrative details include an original closing date of October 1, 2025, an anticipated total of about seven awards, and unrestricted eligibility (meaning the opportunity does not limit applicants to a narrow set of institution types in the provided summary). The award ceiling is not specified in the provided listing. Overall, this mechanism is best suited for teams with a well-integrated, hypothesis-driven melanoma project that can credibly deliver tangible advances in the shorter term, supported by a collaborative plan where each PI brings distinct expertise that strengthens the combined approach.

• The Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Melanoma, Team Science Award" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
• This funding opportunity was created on 2025-05-14.
• Applicants must submit their applications by 2025-10-01. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• The number of recipients for this funding is limited to 7 candidate(s).
• Eligible applicants include: Unrestricted.

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