Opportunity Information: Apply for PA 16 395
The National Institutes of Health (NIH) funding opportunity titled "Secondary Analyses of Alcohol and Chronic Disease (R01)" (Funding Opportunity Number: PA 16-395) supports research projects that use existing, previously collected data to study how alcohol relates to chronic disease. The focus is on secondary data analysis rather than collecting new primary data, with the aim of producing innovative findings in a cost-effective way. The scientific emphasis is on chronic disease etiology and epidemiology, meaning applicants are expected to investigate causes, risk patterns, population-level trends, and relationships between alcohol exposure and chronic disease outcomes using datasets that already exist.
This opportunity uses the R01 mechanism, which is NIH's standard grant program for mature, hypothesis-driven research projects. In practice, that means the application should be built around a clear set of research questions or hypotheses, a strong analytic plan, and convincing justification that the chosen dataset(s) can answer the proposed questions. Since the FOA is specifically about secondary analyses, the value of the project is expected to come from novel approaches to existing data, such as new analytic methods, combining datasets where appropriate, examining understudied subgroups, exploring alcohol-related exposure measurement in more refined ways, or answering questions that were not part of the original purpose of the dataset.
The announcement sits within NIH's broader health research mission and is categorized under education and health activities. It is associated with CFDA numbers 93.273 and 93.399. While the public summary does not provide an award ceiling or expected number of awards, the intent is clear: enable rigorous, efficient research that leverages existing resources to move knowledge forward on alcohol use and chronic disease, rather than funding expensive new data collection efforts.
Eligibility is broad and includes many types of domestic applicants: state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities and Indian housing authorities; Native American tribal organizations that are not federally recognized governments; nonprofits with and without 501(c)(3) status (as long as they are not institutions of higher education); for-profit organizations other than small businesses; small businesses; and additional "other" categories. The FOA also explicitly highlights additional eligible groups and institution types, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, U.S. territories or possessions, and non-U.S. entities (foreign organizations). This wide eligibility signals that NIH is open to strong analytic teams across many sectors and geographies, including organizations that work closely with communities affected by alcohol-related harms and chronic disease disparities.
Key administrative details from the source listing include an original creation date of August 10, 2016, and an original closing date listed as September 7, 2019. The opportunity is labeled as "Discretionary" and uses the "Grant" funding instrument type. Even without the full application instructions shown here, the core expectation is that proposals will identify suitable existing datasets, define alcohol-related exposure variables and chronic disease outcomes clearly, and provide a robust plan for statistical and epidemiologic analysis that can produce meaningful, publishable insights while making efficient use of already collected information.Apply for PA 16 395
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Secondary Analyses of Alcohol and Chronic Disease (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273, 93.399.
- This funding opportunity was created on 2016-08-10.
- Applicants must submit their applications by 2019-09-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs): Secondary Analyses of Alcohol and Chronic Disease (R01) - PA 16-395
What is the title of this NIH funding opportunity?
The funding opportunity is titled "Secondary Analyses of Alcohol and Chronic Disease (R01)".
What is the Funding Opportunity Number (FOA number)?
The FOA number is PA 16-395.
What is the main purpose of this grant opportunity?
This opportunity supports research projects that use existing, previously collected data to study how alcohol relates to chronic disease. The intent is to produce innovative findings in a cost-effective way by leveraging data that already exist rather than collecting new primary data.
What type of research is emphasized in this FOA?
The scientific emphasis is on secondary data analysis focused on chronic disease etiology and epidemiology. That includes investigating causes, risk patterns, population-level trends, and relationships between alcohol exposure and chronic disease outcomes using existing datasets.
Does this opportunity support collecting new primary data?
The focus is on secondary analyses of existing datasets rather than collecting new primary data. The value is expected to come from novel and rigorous analyses of data that have already been collected.
What funding mechanism is used?
This opportunity uses the NIH R01 mechanism, which is NIH's standard grant program for mature, hypothesis-driven research projects.
What does using the R01 mechanism imply for the application?
Because it is an R01, the application is expected to be organized around a clear set of research questions or hypotheses, a strong analytic plan, and a convincing justification that the chosen dataset(s) can answer the proposed questions.
What kinds of projects are a good fit for a secondary analysis R01 like this?
Projects are expected to generate new knowledge from existing data by using novel approaches such as:
- Applying new or improved analytic methods to existing datasets
- Combining datasets where appropriate to answer new questions
- Examining understudied subgroups
- Refining how alcohol exposure is measured within existing data
- Answering questions that were not part of the original purpose of the dataset
What topic areas should the proposed analyses address?
Proposed analyses should address how alcohol exposure relates to chronic disease outcomes, with attention to etiologic and epidemiologic questions such as risk patterns, trends, and exposure-outcome relationships.
What are applicants expected to define clearly in their proposals?
Applicants are expected to clearly define:
- The existing dataset(s) to be used
- Alcohol-related exposure variables
- Chronic disease outcomes
- A robust statistical and epidemiologic analysis plan capable of producing meaningful, publishable insights
Why does the FOA emphasize cost-effective research?
The FOA aims to enable rigorous research that makes efficient use of already collected information, moving knowledge forward without the expense and time associated with new large-scale data collection.
What is the funding instrument type?
The funding instrument type is a Grant.
How is the opportunity categorized administratively?
The opportunity is labeled as Discretionary and sits within NIH's broader mission in health research. It is categorized under education and health activities.
What CFDA numbers are associated with this opportunity?
This opportunity is associated with CFDA numbers 93.273 and 93.399.
Who is eligible to apply?
Eligibility is broad and includes many domestic applicant types, including:
- State, county, and local governments
- Special district governments
- Independent school districts
- Public and state-controlled institutions of higher education
- Private institutions of higher education
- Federally recognized Native American tribal governments
- Public housing authorities and Indian housing authorities
- Native American tribal organizations (other than federally recognized tribal governments)
- Nonprofits with and without 501(c)(3) status (as long as they are not institutions of higher education)
- For-profit organizations other than small businesses
- Small businesses
- Other eligible categories mentioned in the announcement
Are minority-serving institutions specifically identified as eligible?
Yes. The FOA explicitly highlights eligibility for institution types including:
- Alaska Native and Native Hawaiian Serving Institutions
- Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)
- Hispanic-serving Institutions
- Historically Black Colleges and Universities (HBCUs)
- Tribally Controlled Colleges and Universities (TCCUs)
Are faith-based or community-based organizations eligible?
Yes. The FOA explicitly lists faith-based or community-based organizations among the eligible groups and institution types.
Can federal agencies apply?
Yes. The FOA includes eligible federal agencies among the additional eligible groups.
Are U.S. territories or possessions included in eligible applicants?
Yes. The FOA explicitly includes U.S. territories or possessions among the eligible groups.
Are foreign organizations eligible to apply?
Yes. The FOA includes non-U.S. entities (foreign organizations) as eligible applicants.
Does the public summary provide an award ceiling or the expected number of awards?
No. The provided public summary does not include an award ceiling or the expected number of awards.
When was this opportunity originally created?
The original creation date listed is August 10, 2016.
What is the original closing date shown in the source listing?
The original closing date listed is September 7, 2019.
What is the core expectation of a competitive proposal under this FOA?
Based on the description provided, proposals are expected to identify suitable existing datasets, clearly define alcohol exposure measures and chronic disease outcomes, and present a strong, rigorous analytic plan that can produce meaningful and publishable insights while leveraging existing resources.
What does it mean that NIH is "open to strong analytic teams across many sectors and geographies"?
The broad eligibility indicates NIH is open to applications from a wide range of organization types and locations, including groups working closely with communities affected by alcohol-related harms and chronic disease disparities, as long as the project is aligned with the secondary analysis focus and has a strong analytic approach.
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| NCI Mentored Clinical Scientist Research Career Development Award to Promote Diversity (K08) Apply for PAR 16 400 Funding Number: PAR 16 400 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Engineering Next-Generation Human Nervous System Microphysiological Systems (R01) Apply for PAR 16 398 Funding Number: PAR 16 398 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NCI Mentored Patient-Oriented Research Career Development Award to Promote Diversity (K23) Apply for PAR 16 399 Funding Number: PAR 16 399 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NCI Mentored Research Scientist Development Award to Promote Diversity (K01) Apply for PAR 16 401 Funding Number: PAR 16 401 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NLM Express Research Grants in Biomedical Informatics (R01) Apply for PAR 16 404 Funding Number: PAR 16 404 Agency: National Institutes of Health Category: Education, Health Funding Amount: $250,000 |
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| "High" or "Medium" Priority AIDS Research on Non-AIDS-defining or AIDS-defining Cancers (R21) Apply for PA 16 425 Funding Number: PA 16 425 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
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| Strategic Alliances for Medications Development to Treat Substance Use Disorders (R01) Apply for PAR 16 430 Funding Number: PAR 16 430 Agency: National Institutes of Health Category: Education, Health Funding Amount: $3,000,000 |
| Health Promotion Among Racial and Ethnic Minority Males (R21) Apply for PA 16 432 Funding Number: PA 16 432 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Symptom Management in HIV-Infected Individuals with Comorbid Conditions (R01) Apply for PA 16 427 Funding Number: PA 16 427 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Symptom Management in HIV-Infected Individuals with Comorbid Conditions (R21) Apply for PA 16 429 Funding Number: PA 16 429 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
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